Psychiatry 9 , — Sheline, Y. Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Psychiatry 67 , — Wassertheil-Smoller, S. Change in depression as a precursor of cardiovascular events. Peters, R. Association of depression with subsequent mortality, cardiovascular morbidity and incident dementia in people aged 80 and over and suffering from hypertension.
Age Aging. May, H. Depression after coronary artery disease is associated with heart failure. Kato, N. Relationship of depressive symptoms with hospitalization and death in Japanese patients with heart failure. Lesman-Leegte, I. Heart Fail. Frasure-Smith, N. Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure.
Circulation , — Depression following myocardial infarction. Impact on 6-month survival. Glassman, A. Psychiatric characteristics associated with long-term mortality among patients having an acute coronary syndrome and major depression: seven-year follow-up of SADHART participants. Tully, P. The role of depression and anxiety symptoms in hospital readmissions after cardiac surgery. Dao, T. Clinical depression, posttraumatic stress disorder, and comorbid depression and posttraumatic stress disorder as risk factors for in-hospital mortality after coronary artery bypass grafting surgery.
Kendel, F. Predictive relationship between depression and physical functioning after coronary surgery. Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease. Psychiatry 65 , 62—71 Hoen, P. Differential associations between specific depressive symptoms and cardiovascular prognosis in patients with stable coronary heart disease. Davidson, K. Association of anhedonia with recurrent major adverse cardiac events and mortality 1 year after acute coronary syndrome.
Leroy, M. Anhedonia as predictor of clinical events after acute coronary syndromes: a 3-year prospective study. Psychiatry 51 , 8—14 Druss B. Mental disorders and use of cardiovascular procedures after myocardial infaction. Gehi, A. Depression and medication adherence in outpatients with coronary heart disease: findings from the Heart and Soul Study. Rocha V.
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Obesity, inflammation and atherosclerosis. Currier, M. Inflammation and mood disorders: proinflammatory cytokines and the pathogenesis of depression. Raison, C. Raedler, T. Inflammatory mechanisms in major depressive disorder. Psychiatry 24 , — Goldschmidt-Clermont, P. Loss of bone marrow-derived vascular progenitor cells leads to inflammation and atherosclerosis. Heart J. Goldschmidt-Clermont P. On the memory of a chronic illness. Aging Knowledge Environ. Asahara, T. Isolation of putative progenitor endothelial cells for angiogenesis. Science , — Pikhart, H.
Depressive symptoms and levels of C-reactive protein: a population-based study. Psychiatry Psychiatr. Elovainio, M. Depression and C-reactive protein: population-based Health study. Kling, M. Sustained low-grade pro-inflammatory state in unmedicated, remitted women with major depressive disorder as evidenced by elevated serum levels of the acute phase proteins C-reactive protein and serum amyloid A. Douglas, K.
Relationship between depression and C-reactive protein in a screening population. Kuo, H. Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol. Pasco, J.
Association of high-sensitivity C-reaction protein with de novo major depression. Howren, M. Depression, C-reactive protein and two-year major adverse cardiac events in men after acute coronary syndromes. Higher than normal plasma interleukin-6 concentrations in cancer patients with depression: preliminary findings. Lindqvist, D. Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity.
Ferketich, A. Depressive symptoms and inflammation among heart failure patients. Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study. Duivis, H. Depressive symptoms, health behaviors, and subsequent inflammation in patients with coronary heart disease: prospective findings from the Heart and Soul Study. Morris A. Association between depression and inflammation—differences by race and sex.
Mause, S. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Ross R. Atherosclerosis—an inflammatory disease. Lusis A. Nature , — Libby, P. Inflammation in atherosclerosis. Seshiah, P. Activated monocytes induce smooth muscle cell death: role of macrophage colony-stimulating factor and cell contact.
Inflammation, stem cells and atherosclerosis genetics. Weber, A. Platelet-derived microparticles stimulate coronary artery smooth muscle cell mitogenesis by a PDGF-independent mechanism. Ando, M. Circulating platelet-derived microparticles with procoagulant activity may be a potential cause of thrombosis in uremic patients. Kidney Int.
Platelets and coronary heart disease: potential psychophysiologic mechanisms. Exaggerated platelet reactivity in major depression. Platelet reactivity in depressed patients treated with paroxetine: preliminary findings. Psychiatry 57 , — Thiagarajan, P.
Evidence for phosphatidylserine exposure in the procoagulant response of activated platelets. Morel-Kopp, M.
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The association of depression with platelet activation: evidence for a treatment effect. Laghrissi-Thode, F. Psychiatry 42 , — Parakh, K. Platelet function in patients with depression. Depression and platelet activation in outpatients with stable coronary heart disease: findings from the Heart and Soul Study. Aschbacher, K. Persistent versus transient depressive symptoms in relation to platelet hyperactivation: a longitudinal analysis of dementia caregivers.
Atar, D. Escitalopram, but not its major metabolites, exhibits antiplatelet activity in humans. Serebruany, V.
Platelet inhibition by sertraline and N -desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors. D Alderman, C. Abnormal platelet aggregation associated with fluoxetine therapy.
Thrombolysis 27 , 48—56 Tomfohr, L. Symptoms of depression and impaired endothelial function in healthy adolescent women. Lavoie, K. Association between clinical depression and endothelial function measured by forearm hyperemic reactivity. Kim, J. Coronary endothelial dysfunction associated with a depressive mood in patients with atypical angina but angiographically normal coronary artery.
Cooper, D. Though this one might be obvious, but studies have actually proven heartbreak does cause depression. The research found "losses that involved lower self-esteem were twice as likely to trigger depression as ones that involved loss alone. As I mentioned before, love is just as addicting as drugs, specifically cocaine. When you're a cocaine addict cut off from the drug, your body goes through withdrawal.
The same thing happens when you're addicted to love and suddenly find yourself without it.
"HEARTACHE VS. HEARTBREAK" LYRICS by OZMA: Heartache will get you
According to The Frisky , "areas of the brain are much more active after seeing the image of the ex. These same active areas are also afire in cocaine addicts who are experiencing physical pain while going through withdrawal. Luckily, like the withdrawal you experience from drugs, eventually the symptoms will subside and you can get on with your new, single life. It'll be better, I promise. Doctors say after a terrible breakup, you can question your identity.
According to Erica Slotter , a psychology Ph. When a relationship ends, that sense of self ends. Breakups can provoke existential crises. When we're brutally broken up with, we're left questioning who we are because we're not sure how this could have happened to us. Wasn't that person The One? Now you're forced into a new phase of life, you'll have to figure out just what kind of person you want to be moving forward.
Mallonee , licensed mental health counselor, tells Bustle. And how can you tell if your marathon-watching is healing, or starting to look like depression? The reason it's all so confusing is largely because heartbreak looks a lot like other diagnoses. Mental health and other "protective factors," which include emotional support systems, access to medical care, spiritual beliefs, and employment stability, can make healing from heartbreak easier, Parisi says.
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But if you're missing some of those supports, the pain can be multiplied. While any symptom that is particularly debilitating or long-lasting can be a reason to seek help, mental health professionals agree that there are particular indicators that your heartbreak is turning into more serious. Here are 11 signs your heartbreak is more than it seems, according to experts. It's normal to feel heartbreak in your body. But if the feelings in your body keep sticking around or getting worse, it might be a sign that you need more help than you're receiving.
This could look like getting sick easily, eating too much or too little, or developing a rash or headaches, says Solomita. Your physical and mental health are inextricably linked , so it's important to take care of them both, especially in times when you need resiliency most. It makes sense for your ex to be running through your thoughts. But when they're genuinely all you can think about, it's time to reassess. Moreover, it's necessary to keep track of when things go from how they usually are, to noteworthy, to potentially alarming.
Similarly, if you start to feel like you're worthless or unlovable after a breakup, that indicates your heartbreak is moving into territory best navigated with help," Brennan C. If you find yourself going down either of those paths, support is definitely a good idea. Even once you've found a healthy balance, you may still experience some of the symptoms of heartbreak, but they can start to fade away. Maintaining and supporting friendships in the wake of a major breakup can be unbelievably difficult. Although they're some of the most important people in your life, friends are not trained professionals and may not know how to give you the support you need.
The lessons of heartache and heartbreak.
If they're not giving you what you need, avoiding your friends is still not the best bet. And if you do still keep hanging around them, but don't feel quite right, don't blame yourself. It's OK to acknowledge that your friends can't solve everything. There's no shame going to a neutral third party therapist, counselor, etc to get through this with a little more ease.